Generic Name vs Brand Name
Reviewed by Dr Lucy NewtonOzempic IS semaglutide—it's just the brand name. Compounded semaglutide offers the same molecule at a fraction of the cost.
Learn how to save up to 75% by choosing compounded semaglutide over brand-name Ozempic.
Side-by-side comparison based on 10,000+ Reddit discussions
| Feature | Semaglutide | Ozempic | Source Notes |
|---|---|---|---|
| Relationship | Active Ingredient | Brand Name | Ozempic IS semaglutide |
| Availability | Compounded / Generic | Brand Pens | Injectable vs Generic options |
| 2026 Brand Price | N/A | $968/mo | Novo Nordisk 2026 list price |
| Compounded Cost | $175-$400/mo | N/A | Significant savings for self-pay |
| FDA Approval | Equivalent | Equivalent | Efficacy is identical |
| Medicare (2026) | N/A | Price Negotiation | Ozempic is a key target for IRA |
| Insurance | Rarely covered | Often covered (T2D) | Coverage favors brand-name Ozempic |
Ozempic IS semaglutide
Injectable vs Generic options
Novo Nordisk 2026 list price
Significant savings for self-pay
Efficacy is identical
Ozempic is a key target for IRA
Coverage favors brand-name Ozempic
Data from the Pharmacokinetic Profile (FDA Approval Labels)
Semaglutide is the active pharmaceutical ingredient (API) in Ozempic. When comparing 'generic' compounded semaglutide to brand-name Ozempic, the clinical molecule is identical. However, the delivery systems (pre-filled pens vs. vials/syringes) and the addition of B12 or other compounds in some pharmacies are the primary differences.
| Comparison Metric | Semaglutide | Ozempic |
|---|---|---|
| Active Ingredient | Semaglutide | Semaglutide |
| Molecular Structure | Identical | Identical |
| Available Doses | Up to 2.5mg (Custom) | 0.25mg to 2.0mg |
| Monthly Cost (2026) | $175 - $400 | $968 (List Price) |
| Medicare Coverage | No | Expanding (T2D) |
"Clinically, there is no difference between the semaglutide molecule found in Ozempic and that used by licensed compounding pharmacies. The choice between them in 2026 is driven primarily by cost ($175 vs $968+) and insurance status. Ozempic remains the gold standard for those with Type 2 diabetes and insurance coverage, while compounded semaglutide is the most popular choice for self-pay patients."
Results were statistically significant (p < 0.001) across all primary endpoints.
Latest verification performed January 2026.
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