We ranked GLP-1 programs by starting monthly price, weighing cost against medication quality, physician oversight, and overall value.
Walgreens Weight Management charges $49/month for program access with no separate membership fee. Their nationwide pharmacy network allows in-store medication pickup, and the program focuses on brand-name GLP-1 prescriptions with insurance support.
WeightWatchers Clinic starts at $74/month and bundles GLP-1 medication access with the WW app, coaching sessions, and community support groups. Compounded medication options are available alongside their behavioral weight management program.
Mayo Clinic Diet starts at $50/month and includes structured meal planning, a coaching app, and GLP-1 medication support developed by Mayo Clinic physicians. The program operates fully online with no in-person visits required.
Livea charges $69/month and operates across 60+ Midwest clinic locations plus telehealth. The program includes one-on-one coaching, personalized meal planning, and medically supervised GLP-1 prescriptions.
Maximus provides compounded semaglutide at $80/month for male patients with no separate membership fee. They also offer testosterone optimization alongside GLP-1 treatment through their men-focused telehealth platform.
PlushCare charges $20 per consultation and accepts insurance for brand-name GLP-1 medications like Wegovy and Zepbound. A $19.99/month membership is required. They provide prior authorization support for insured patients.
Hello Alpha offers GLP-1 programs starting at $79/month through their women-focused telehealth platform. Consultations are async in most states, meaning no video appointment is required. Compounded GLP-1 medications are available.
Sesame Care uses a pay-per-visit model for GLP-1 consultations with no mandatory membership or subscription fee. The total cost including consultation and compounded medication starts around $99/month.
GobyMeds sells 12-week starter bundles that work out to approximately $100/month for compounded semaglutide and $133/month for tirzepatide. They source from 503B pharmacies and ship overnight with refrigerated packaging.
Pomegranate Health offers compounded semaglutide at $119/month with B12 included and compounded tirzepatide at $179/month with B6 for nausea management. There are no contracts or long-term commitments required.
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The cheapest GLP-1 programs start at $49–$80/month. Walgreens starts at $49/month for program access, Maximus offers compounded semaglutide at $80/month for men, and Livea starts at $69/month with coaching included. The true lowest cost depends on whether you have insurance coverage for brand-name GLP-1s.
Brand-name GLP-1 medications like Wegovy ($1,349/month) and Zepbound ($1,069/month) are expensive without insurance. Compounded versions use the same active ingredient but are made by compounding pharmacies, cutting out brand-name markup — resulting in costs of $80–$350/month.
Price alone does not determine safety. Look for programs using FDA-registered compounding pharmacies (503A or 503B), physician oversight, and clear titration protocols regardless of cost. Some of the most affordable programs on this list use the same quality pharmacies as premium programs.
Yes — some programs like PlushCare and Cleveland Clinic accept insurance for brand-name GLP-1 medications. Coverage varies by insurer and state. A prior authorization process is typically required. Programs with insurance concierge services can help navigate this.