HIGHLY RECOMMENDED
Drugs: Compounded semaglutide and tirzepatide (both injectable and sublingual drops). Starting price:$147/month for injectable semaglutide (promotional), with sublingual drops at $149/month.
Direct Meds delivers exceptional value with all-inclusive pricing that covers medication, supplies, physician consultations, 1-day shipping, and ongoing nurse support - no membership fees or hidden costs. Tirzepatide options start at $349/month for sublingual drops, with injectable tirzepatide offering a $150 promotional discount.
Customer satisfaction appears genuinely strong based on reported 4.6 Trustpilot rating from 6,172 reviews (82% 5-star), with 53,000+ customers served. Individual representatives are frequently praised by name for going above and beyond expectations.
The included nurse support throughout your treatment journey is a real differentiator at this competitive price point. Lab work is not included - the company advises maintaining regular monitoring with your primary care physician for safety.
Budget-conscious users who want affordable GLP-1 access with real human support from named representatives and included nurse care
Those who require FDA-approved brand-name medications only, prefer in-person consultations, or need included lab work in their program
Exceptional value with pricing starting at $147/month for injectable semaglutide - includes medication, supplies, shipping, AND nurse support. Representatives consistently praised by name in thousands of reviews.
Multi-month bundles require upfront commitment; phone cancellation required (standard for telehealth)
Regular Price
$297/month
Promotional Price
$147/month (promotional)
Dosing: Once weekly subcutaneous injection
Included: Medication, supplies, physician consultation, 1-day shipping, nurse support
Same active ingredient as Ozempic/Wegovy but NOT FDA-approved
Regular Price
$179/month
Promotional Price
$149/month (promotion)
Dosing: Daily sublingual administration
Included: Medication, physician consultation, shipping, nurse support
Needle-free option for patients who prefer oral administration
Regular Price
$399/month
Promotional Price
-$150 (promotion)
Dosing: Once weekly subcutaneous injection
Included: Medication, supplies, physician consultation, 1-day shipping, nurse support
Same active ingredient as Mounjaro/Zepbound but NOT FDA-approved
Regular Price
$224/month
Promotional Price
$349/month
Dosing: Daily sublingual administration
Included: Medication, physician consultation, shipping, nurse support
Needle-free tirzepatide option
| Product | Regular Price | Promo Price | State Variations |
|---|---|---|---|
| Semaglutide Injectable | $297-$347/month | $147/month | Available in all US states except MS and LA |
| Semaglutide Sublingual | $249/month (starting) | $149/month (promotion) | Available in all US states except MS and LA |
| Tirzepatide Injectable | $497-$547/month | -$150 (promotion) | Available in all US states except MS and LA |
| Tirzepatide Sublingual | $399/month | $349/month | Available in all US states except MS and LA |
Physician Consultation
Normally $99/visit but bundled into monthly price
Injection Supplies
Syringes, alcohol wipes included
Shipping
1-day FedEx or UPS in temperature-controlled packaging
Nurse Support
Ongoing access to licensed nurses for questions and dose adjustments
Lab Work
Company advises maintaining regular monitoring with primary care physician
Injectable semaglutide starting at $147/month, sublingual at $149/month - among lowest in industry. All-inclusive pricing includes consultation, supplies, shipping, and nurse support.
Impact: Makes GLP-1 medications accessible to budget-conscious users who might otherwise be priced out of treatment
4.6/5 Trustpilot rating with 6,172 reviews, 82% 5-star reviews. Company responds to 97% of negative reviews.
Impact: Majority of customers have positive experiences; company actively engages with feedback
Licensed nursing team included in all plans for ongoing support, dose adjustments, and side effect management
Impact: Provides human support throughout weight loss journey without additional cost
1-day shipping via FedEx/UPS in temperature-controlled packaging. Same-day shipping for prescriptions received before 2 PM CT.
Impact: Quick medication delivery reduces treatment interruptions
Both injectable and sublingual formulations available for semaglutide and tirzepatide
Impact: Needle-free options available for patients who prefer oral administration
Direct Meds demonstrates strong performance across all metrics: 4.6/5 Trustpilot from 6,172+ reviews (82% 5-star), LegitScript certified, 53,000+ customers served, exceptional value pricing with included nurse support.
Impact: Customers benefit from responsive support, fast 1-day shipping, and included nurse care throughout their journey.
4.5 Trustpilot rating, $249/month semaglutide, no FDA warning letters, strong nurse support
Public company, broader platform, $199+/month pricing, though also received FDA warning letter
Offers FDA-approved Wegovy and Zepbound, insurance support, though at higher price point
Even lower promotional pricing available, though with different service models
Complete 60-second online health quiz
Provide detailed medical history through secure intake form
Licensed provider reviews responses (typically within 5-24 hours)
If approved, prescription compounded at certified U.S. pharmacy
Medication shipped within 1 business day with tracking
Receive ongoing nurse check-ins and support
Time to First Prescription
Most patients approved same day; 3-4 days from application to treatment start
Consultation Format
Asynchronous review of intake form by licensed provider; some patients report phone follow-up calls
Provider Type
Licensed physicians and nurse practitioners
Video Option
Not standard; primarily asynchronous consultation model
"I had a great experience with Season Whistleton. I had a big issue that was complicated, and she stayed on the phone and sorted each one to a positive resolution."
— Trustpilot review, January 2026
Quality Concerns: Compounded medications are NOT FDA-approved. FDA warning letter noted claims implying products are 'same' as FDA-approved drugs are misleading.
4.6/5
6,172
82% 5-star, 5% 4-star, 2% 3-star, 2% 2-star, 9% 1-star. Company responds to 97% of negative reviews.
4.5/5
5,038
Merged profile from alternate domain - now combined with main profile
F
Multiple reviews
F rating primarily due to 1 unanswered complaint and 104 total complaints. Not accredited.
Mixed
N/A
Industry review highlights affordability as strength, customer service as weakness
"I am 50 years old and I have been on GLP-1 Medicine since October and I have lost 35 pounds. I have struggled with this 35 pound for the last 4 years.. and this medication just helps quiet the hunger in my head."
— Trustpilot video testimonial, Carly B
Resolved Issue
"Had a question about my billing and the team resolved it quickly. Customer Service Manager reached out personally."
— BBB Complaint, resolved satisfactorily
(888) 696-7176 - Operating hours 7AM-7PM daily; some customers report long hold times (over 1 hour mentioned in complaints)
help@directmeds.com
Available on website; some customers report chat is less helpful than phone
Patient portal for account management, intake forms, and dosage requests
Based on Trustpilot reviews and BBB complaints
Best Case
Same-day response with named representatives resolving issues
Typical
24-48 hours for email responses; phone holds can be lengthy
Worst Case
Occasional delays during high-volume periods
Patient safety risk is similar to other compounded GLP-1 telehealth providers. Company uses licensed providers and certified pharmacies. The FDA warning letter addressed marketing claims, not medication safety concerns. Nurse support inclusion is a positive safety factor.
Financial risk is manageable with careful attention to subscription terms and documentation of all communications. The cancellation difficulties documented in complaints are the primary financial risk factor.
Service quality is generally good based on majority of reviews, but the company's rapid growth has created customer service bottlenecks. Most issues are eventually resolved but require customer persistence.
Auto-Renewal
Monthly auto-renewal by default; subscribe-and-save discounts available for longer commitments
Billing Transparency
GOOD - Company offers all-inclusive pricing with no hidden fees. Multi-month bundle terms explained at checkout.
Payment Methods
Credit/debit cards, HSA/FSA accepted
Financing
Not mentioned
"Compounded medications are not FDA-approved. They are prepared by licensed compounding pharmacies under the supervision of healthcare providers. These formulations may differ in safety, effectiveness, and quality from FDA-approved products."
— Direct Meds website disclaimer
State Restrictions
None identified - claims to serve all 50 states
State-Specific Requirements
Partners with licensed providers in each state
Pharmacy Board Actions
No state pharmacy board actions found
LegitScript certified with licensed providers and 503A pharmacies; included nurse support is exceptional; compounded medications standard for telehealth
Among the absolute lowest-priced GLP-1 telehealth options; all-inclusive pricing with no hidden fees includes nurse support, supplies, and shipping
Clear pricing model; FDA warning letter for marketing language common across industry (55 companies cited); company has updated disclosures
Exceptional individual representatives praised by name across thousands of reviews; 97% response rate to negative reviews; dedicated Customer Service Manager
Responds to 97% of negative reviews; 82% 5-star rating reflects strong satisfaction; BBB complaints typical for scale (53,000+ customers)
Direct Meds delivers outstanding value with some of the most competitive GLP-1 pricing in the telehealth market and genuinely impressive customer satisfaction (4.6 Trustpilot from 6,172+ reviews with 82% 5-star ratings). With 53,000+ customers served, individual customer service representatives are frequently praised by name (Chelsea, Zach, Mike Larry, Coco Williams), and the included nurse support adds real ongoing value. LegitScript certified with licensed providers and 503A pharmacies ensures quality care. Best for budget-conscious users who want affordable GLP-1 access with real human support and included nurse care.
Best Alternative: Fridays Health — Similar strong ratings, slightly higher pricing ($249/month), also offers excellent nurse support
Others: MEDVi ($179+, 4.5 from 9K reviews, similar FDA warning), Hims & Hers ($199+, established brand), Ro Body Program (FDA-approved options at higher price)
We verified: LegitScript certification status, BBB rating and complaint history, FDA warning letter (September 9, 2025), Trustpilot review volume and ratings, Company registration (Utah LLC, May 2024), Published pricing on company website.
We could not verify: Specific pharmacy partners used, Third-party testing protocols, Current FDA warning letter compliance status, Total customer count accuracy, Individual customer service experiences beyond documented reviews.
This review is based on publicly available information including company websites, regulatory filings, customer reviews, and third-party reports.
This review is for informational purposes only and does not constitute medical advice. Consult a qualified healthcare provider before starting any weight loss medication.
AllGLP1.com may receive affiliate compensation for referrals. This does not influence our editorial ratings or recommendations.
