The most common side effects of GLP-1 medications are gastrointestinal, and most people experience at least some of them, especially in the first few weeks or after a dose increase.
The ones reported most often:
Less common but worth knowing about: gallbladder issues, pancreatitis, severe dehydration from prolonged vomiting or diarrhea, and a small theoretical risk relating to thyroid C-cell tumors that has only been seen in rodent studies. The FDA labels for these medications include a contraindication for people with a personal or family history of medullary thyroid cancer or MEN2.
Most side effects fade within 4 to 8 weeks as your body adjusts, and they tend to flare again briefly after each dose increase before settling. Eating smaller portions, slowing down at meals, staying hydrated, and prioritizing protein and fiber tends to help. If side effects are severe, persistent, or stopping you from eating and drinking enough, talk to your provider. They may slow your titration, hold you at a lower dose, or switch you to a different GLP-1 if needed.
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The most common side effects of GLP-1 medications are gastrointestinal, and most people experience at least some of them, especially in the first few weeks or after a dose increase.
The ones reported most often:
Less common but worth knowing about: gallbladder issues, pancreatitis, severe dehydration from prolonged vomiting or diarrhea, and a small theoretical risk relating to thyroid C-cell tumors that has only been seen in rodent studies. The FDA labels for these medications include a contraindication for people with a personal or family history of medullary thyroid cancer or MEN2.
Most side effects fade within 4 to 8 weeks as your body adjusts, and they tend to flare again briefly after each dose increase before settling. Eating smaller portions, slowing down at meals, staying hydrated, and prioritizing protein and fiber tends to help. If side effects are severe, persistent, or stopping you from eating and drinking enough, talk to your provider. They may slow your titration, hold you at a lower dose, or switch you to a different GLP-1 if needed.
The most common side effects of GLP-1 medications are gastrointestinal, and most people experience at least some of them, especially in the first few weeks or after a dose increase.
The ones reported most often:
Less common but worth knowing about: gallbladder issues, pancreatitis, severe dehydration from prolonged vomiting or diarrhea, and a small theoretical risk relating to thyroid C-cell tumors that has only been seen in rodent studies. The FDA labels for these medications include a contraindication for people with a personal or family history of medullary thyroid cancer or MEN2.
Most side effects fade within 4 to 8 weeks as your body adjusts, and they tend to flare again briefly after each dose increase before settling. Eating smaller portions, slowing down at meals, staying hydrated, and prioritizing protein and fiber tends to help. If side effects are severe, persistent, or stopping you from eating and drinking enough, talk to your provider. They may slow your titration, hold you at a lower dose, or switch you to a different GLP-1 if needed.
The most common side effects of GLP-1 medications are gastrointestinal, and most people experience at least some of them, especially in the first few weeks or after a dose increase.
The ones reported most often:
Less common but worth knowing about: gallbladder issues, pancreatitis, severe dehydration from prolonged vomiting or diarrhea, and a small theoretical risk relating to thyroid C-cell tumors that has only been seen in rodent studies. The FDA labels for these medications include a contraindication for people with a personal or family history of medullary thyroid cancer or MEN2.
Most side effects fade within 4 to 8 weeks as your body adjusts, and they tend to flare again briefly after each dose increase before settling. Eating smaller portions, slowing down at meals, staying hydrated, and prioritizing protein and fiber tends to help. If side effects are severe, persistent, or stopping you from eating and drinking enough, talk to your provider. They may slow your titration, hold you at a lower dose, or switch you to a different GLP-1 if needed.