✅ HIGHLY RECOMMENDED - Sesame is a top-tier telehealth platform with the industry's best medication selection, strongest professional recognition (Healthline #1 five years running), and excellent 4.5/5 Trustpilot rating. Ideal for users with insurance coverage or those wanting FDA-approved brand-name medications.
Drugs: Wegovy, Zepbound, Mounjaro, Ozempic, Rybelsus, Saxenda, Contrave, Metformin, Topiramate, and more (14 total weight loss medications). Regular Monthly Price: $448/month ($99 subscription + $349 Wegovy self-pay). Lowest Monthly Price: $298/month ($99 subscription + $199 introductory Wegovy pricing).
Sesame Care operates as a healthcare marketplace where you choose from board-certified doctors, earning a 4.5/5 rating on Trustpilot from over 3,600 reviews. The Success by Sesame program costs $99/month (billed every 28 days) and includes telehealth visits, unlimited messaging, and labs in most states.
Unlike competitors offering compounded medications, Sesame specializes in FDA-approved brand-name GLP-1s with insurance billing support. With insurance coverage, medications like Wegovy, Zepbound, and Mounjaro cost just $25/month. Self-pay options include Wegovy at $349/month (or $199/month for first 2 months) and affordable Zepbound vials at $349-$499/month.
Total costs can be significant without insurance, as brand-name GLP-1s like Zepbound pens and Mounjaro reach $1,000+ monthly. However, Sesame offers the most comprehensive medication selection in telehealth weight loss, making it ideal for users wanting authentic FDA-approved medications rather than compounded alternatives.
Users who want FDA-approved brand-name GLP-1 medications, those with insurance coverage for weight loss medications, and anyone who values choosing their own provider from a marketplace of board-certified doctors
Those seeking the lowest out-of-pocket cost (medication costs are separate from subscription), users who want compounded semaglutide or tirzepatide, or anyone preferring an all-inclusive pricing model
Offers 14 different weight loss medications including FDA-approved brand-name GLP-1s with insurance billing support - most comprehensive medication selection in the telehealth weight loss space
Medication costs are separate from the $99/month subscription, which means total costs can be significantly higher than competitors offering all-inclusive compounded GLP-1 programs. Brand-name GLP-1s can cost $500-$1,000+/month without insurance.
Regular Price
$349/month (self-pay)
Promotional Price
$199/month for first 2 months (new self-pay patients; lowest doses only)
Dosing: Weekly injection
Included: FDA-approved for chronic weight management
$25/month with insurance coverage. First oral GLP-1 pill (Wegovy pill) also available.
Regular Price
$1,060/month (without insurance)
Promotional Price
N/A
Dosing: Weekly injection
Included: FDA-approved dual GLP-1/GIP receptor agonist for obesity
$25/month with insurance coverage.
Regular Price
$349/month (2.5mg) or $499/month (5mg)
Promotional Price
N/A
Dosing: Weekly injection (self-administered from vial)
Included: Single-dose vials through LillyDirect/Gifthealth integration
Self-pay only, no insurance accepted for vials. Most affordable brand-name tirzepatide option.
Regular Price
$1,079/month (without insurance)
Promotional Price
N/A
Dosing: Weekly injection
Included: FDA-approved for type 2 diabetes, prescribed off-label for weight loss
$25/month with insurance coverage.
Regular Price
$349/month (self-pay program)
Promotional Price
$199/month for first 2 months (new self-pay patients; lowest doses only)
Dosing: Weekly injection
Included: FDA-approved for type 2 diabetes, prescribed off-label for weight loss
$25/month with insurance coverage.
Regular Price
Contact for pricing
Promotional Price
N/A
Dosing: Daily oral tablet
Included: First oral GLP-1 medication
Must be taken on empty stomach. 10-15% potential weight loss.
Regular Price
Contact for pricing
Promotional Price
N/A
Dosing: Daily injection
Included: FDA-approved for weight management
Limited availability through 2025 due to national shortages.
Regular Price
Contact for pricing
Promotional Price
N/A
Dosing: Daily oral
Included: Combination medication for chronic weight management
Good alternative for those who cannot take GLP-1s.
Regular Price
Contact for pricing
Promotional Price
N/A
Dosing: Daily oral
Included: Classic diabetes medication with modest weight loss benefits
Often used as first-line treatment or combined with other medications.
Regular Price
Contact for pricing
Promotional Price
N/A
Dosing: Daily oral
Included: Off-label for weight loss, originally for seizures
Often combined with other therapies to suppress appetite.
| Product | Regular Price | Promo Price | State Variations |
|---|---|---|---|
| Success by Sesame Subscription | $99/month | N/A | Billed every 28 days. Does not include medication costs. |
| Zepbound Vials (LillyDirect) | $349-$499/month | N/A | Self-pay only, most affordable brand tirzepatide |
| Wegovy (with insurance) | $25/month | N/A | Requires insurance coverage and prior authorization |
| Wegovy (self-pay) | $349/month | $199/month for first 2 months | New patient promotional pricing |
| Brand GLP-1s (without insurance) | $1,060-$1,079/month | N/A | Zepbound pens, Mounjaro |
Success by Sesame Subscription
Includes telehealth visits, unlimited messaging, labs in most states
Medication (separate)
GLP-1s range from $25/month (insured) to $1,000+/month (uninsured)
Labs
Nine states may have additional lab fees
Shipping
Home delivery available or pickup at local pharmacy
14 different weight loss medications including Wegovy, Zepbound, Mounjaro, Ozempic, Rybelsus, Contrave, metformin, and more.
Impact: Providers can tailor treatment to individual needs rather than one-size-fits-all approach.
4.5/5 Trustpilot rating with 3,600+ reviews. BBB A rating. Healthline #1 for overall care 2021-2025.
Impact: Confidence in choosing an established, well-reviewed provider.
Marketplace model lets patients browse providers by specialty, experience, and patient reviews before booking.
Impact: More control over healthcare experience than random provider assignment.
Providers assist with insurance prior authorization. GLP-1s as low as $25/month with insurance coverage.
Impact: Potentially dramatic cost savings for insured patients.
LillyDirect integration offers Zepbound single-dose vials at $349-$499/month - most affordable brand tirzepatide available.
Impact: Access to brand-name tirzepatide at fraction of prefilled pen cost.
Does not offer compounded semaglutide or tirzepatide. All medications are FDA-approved.
Impact: Eliminates concerns about compounding quality and FDA regulatory actions.
Brand GLP-1s cost $500-$1,000+/month without insurance, plus $99/month subscription.
Impact: Can be 3-5x more expensive than compounded GLP-1 providers for uninsured users.
Does not offer compounded semaglutide or tirzepatide.
Impact: Users seeking affordable compounded GLP-1s must look elsewhere.
Bills every 28 days instead of monthly, resulting in 13 charges per year.
Impact: Higher annual cost than expected and budgeting challenges.
Marketplace model means provider quality depends on individual selection. Some complaints about no-shows.
Impact: Requires research to select good providers; poor choices may require rebooking.
Hims offers compounded semaglutide at $199/month all-inclusive - significantly lower than Sesame's subscription plus medication costs for uninsured users.
Ro offers a 30-day money-back guarantee for risk-free trial.
Calibrate combines GLP-1 prescriptions with dedicated coaching, nutrition education, and lifestyle support.
Eden's 'Same Price at Every Dose' guarantee keeps monthly cost flat as dosage increases.
Complete online questionnaire about health history, current medications, and weight loss goals
Browse and select your preferred provider from Sesame's marketplace
Schedule video consultation with chosen provider
Discuss medical history and treatment options during video visit
Provider orders labs if medically necessary (covered through Quest Diagnostics in most states)
If appropriate, provider prescribes from 14 available weight loss medications
Choose home delivery or pickup at local pharmacy
Access unlimited messaging and follow-up visits through subscription
Time to First Prescription
Same-day prescriptions possible if medically appropriate. Video consultations available quickly, often same-day appointments.
Consultation Format
Video consultations with provider of your choice. Marketplace model means you can read reviews and select providers based on specialty, experience, and patient ratings.
Provider Type
Network of independently licensed board-certified physicians, nurse practitioners, and physician assistants. You choose your provider from the marketplace.
Video Option
Required. Video consultations are standard for weight loss program.
Quality Concerns: All medications are FDA-approved brand-name products, eliminating compounding quality concerns. However, supply shortages affect availability of some medications like Trulicity, Saxenda, and Victoza.
4.5/5 stars
3,600+ reviews
Strong rating with high review volume. Company responds to 93% of negative reviews. Active Trustpilot subscription indicates engagement.
A rating, BBB Accredited
107 complaints (3 years)
Accredited since 2022. A rating despite complaint volume indicates satisfactory resolution patterns.
#1 Overall Care
Professional review
Ranked #1 for overall care 2021, 2022, 2023, 2024, and 2025.
Best for Doctor Choice
Professional review
Named Best for Doctor Choice 2023, 2024, and 2025.
"I was in dire straits and was amazed I could get an appointment so quick. The price was the best around. The doctor was helpful and knowledgeable. I was able to get a script and have it filled in no time. From the time I booked the appointment and got my script it was less than 2 hours."
— Trustpilot verified review
Billing Issues
"This company is a scam! I paid for an office visit and the premium package. When the PA got on the call she was beyond unprofessional. The call didn't last but 3 mins."
— BBB complaint
(877) 947-6411. Phone support available during business hours.
support@sesamecare.com
Unlimited messaging with your provider through the platform. Customer support chat also available.
Full patient portal and mobile app for appointment booking, messaging, and account management.
Analysis of 3,600+ Trustpilot reviews and BBB complaints
Best Case
Many users report same-day appointments, quick prescription fulfillment, and responsive providers who address concerns promptly.
Typical
Most users report positive experiences with provider quality and platform ease of use. Company responds to 93% of negative Trustpilot reviews.
Worst Case
Some complaints about customer support response times for billing issues, provider no-shows, and prescription errors requiring additional appointments.
Patient safety risk is low. FDA-approved medications and licensed providers ensure standard medical care protocols.
Financial risk is moderate. Clear on subscription pricing but total costs with medication can be higher than expected. Insurance coverage significantly reduces risk.
Service risk is low. Established company with strong reviews and active customer engagement.
Auto-Renewal
Yes - Success by Sesame subscription auto-renews every 28 days (not monthly). Can cancel anytime.
Billing Transparency
MODERATE - Pricing shown before booking is clear. However, 28-day billing cycle means 13 charges per year, which surprises some users. Medication costs separate from subscription.
Payment Methods
Credit card, debit card. HSA/FSA eligible. Sesame Rx savings card available for up to 80% off prescriptions.
Financing
No formal financing. 28-day billing cycle for subscription. Individual appointment pricing available without subscription.
"I have been using Sesame Care for about two years and can't thank them enough for all the time and money I have saved. The doctors are always caring, on time and attentive to my concerns."
— BBB customer review
State Restrictions
Available in all 50 states. Provider availability may vary by location.
State-Specific Requirements
Providers are independently licensed in applicable states. Labs through Quest Diagnostics not included in nine states.
Pharmacy Board Actions
No pharmacy board actions documented. Uses licensed pharmacies for fulfillment.
Excellent value for insured users ($25/month GLP-1s possible). Zepbound vials at $349-499 are most affordable brand tirzepatide anywhere. $99/month subscription competitive for comprehensive care.
FDA-approved medications only. Board-certified providers. Video consultations. Labs when needed. Strong safety profile.
Responds to 93% of negative reviews. 4.5/5 Trustpilot with 3,600+ reviews demonstrates consistent quality. Phone, email, and unlimited messaging support.
14 different weight loss medications - most comprehensive selection available. FDA-approved brand-names including all major GLP-1s.
BBB Accredited with A rating. 8+ years in business. Transparent pricing. Backed by GV, General Catalyst, Virgin Group. Official Costco telehealth partner.
Sesame stands out as one of the best telehealth platforms for GLP-1 weight loss treatment. With a 4.5/5 Trustpilot rating from 3,600+ reviews, Healthline's #1 ranking for overall care five consecutive years (2021-2025), and the industry's most comprehensive medication selection (14 options), Sesame delivers premium quality. The unique marketplace model lets you choose your own provider - a feature no competitor matches. For insured users, GLP-1s can cost as little as $25/month, making this potentially the most affordable option. The Zepbound vial program ($349-499/month) offers the cheapest brand-name tirzepatide available anywhere. While uninsured users may find better value with compounded options from competitors, Sesame excels for those who want FDA-approved medications, insurance support, and provider choice. Rating: 4.5/5 - HIGHLY RECOMMENDED
Best Alternative: Hims & Hers — For uninsured users seeking lowest total cost. $199/month all-inclusive compounded semaglutide vs Sesame's $99 subscription plus $500-$1,000+ medication.
Others: Eden (flat-rate pricing at all doses), Ro Body Program (money-back guarantee), Calibrate (comprehensive coaching), Remedy Meds (all-inclusive compounded options)
We verified: Trustpilot rating (4.5/5, 3,600+ reviews), BBB accreditation and A rating, Founded 2018, headquartered New York, Funding from GV, General Catalyst, Virgin Group, $99/month subscription pricing, Zepbound vial pricing ($349-$499/month), 28-day billing cycle, 14 medication options, Healthline #1 ranking 2021-2025.
We could not verify: Exact total user count, Insurance approval success rates, Average weight loss outcomes.
This review is based on publicly available information including Trustpilot reviews, BBB profile, official company materials, and third-party review sites. We have not received payment from Sesame for this review.
This review is for informational purposes only and does not constitute medical advice. GLP-1 medications require prescription and should only be used under medical supervision. Consult a healthcare provider before starting any medication.
AllGLP1.com may earn affiliate commissions from providers mentioned in this review. This does not influence our editorial ratings or factual assessments.
